PHARMACEUTICAL MICROBIOLOGY

135.00

Authors Name S. B. Bhise , M. S. Bhise , Lalit Lata Jha
Edition First
Publishing Year Jun-19
Pages 150
ISBN 9789388897754
Language English
Ebook Link

Only Printed Book Is Available

Syllabus

 

Unit I                                                                                             10 Hours

Introduction, history of microbiology, its branches, scope and its importance.

Introduction to Prokaryots and Eukaryots.

Study of ultra-structure and morphological classification of bacteria.

Nutritional requirements, raw materials used for culture media and physical parameters for growth, growth curve, isolation and preservation methods for pure cultures, cultivation of anaerobes, and quantitative measurement of bacterial growth (total and viable count).

Study of different types of phase contrast microscopy, dark field microscopy and electron microscopy.

Unit II                                                                                            10 Hours

Identification of bacteria using staining techniques (Simple, Gram’s and Acid-fast staining) and biochemical tests (IMViC).

Study of principle, procedure, merits, demerits and applications of physical, chemical and mechanical methods of sterilization.

Evaluation of the efficiency of sterilization methods.

Equipments employed in large scale sterilization.

Sterility indicators.

Unit III                                                                                           10 Hours

Study of morphology, classification, reproduction/replication and cultivation of Fungi and Virus.

Classification and mode of action of disinfectants.

Factors influencing disinfection, antiseptics and their evaluation for bacteriostatic and bactericidal actions.

Evaluation of bacteriostatic and bactericidal agents.

Sterility testing of products (solids, liquids, ophthalmic and other sterile products) according to IP, BP and USP.

Unit IV                                                                                           08 Hours

Designing of aseptic area, laminar flow equipments; study of different sources of contamination in an aseptic area and methods of prevention, clean area classification.

Principles and methods of different microbiological assay. Methods for standardisation of antibiotics, vitamins and amino acids.

Assessment of a new antibiotic and testing of anti-microbial activity of a new substance.

General aspects- environmental cleanliness.

Unit V                                                                                            07 Hours

Types of spoilage, factors affecting the microbial spoilage of pharmaceutical products, sources and types of microbial contaminants, assessment of microbial contamination and spoilage.

Preservation of pharmaceutical products using antimicrobial agents, evaluation of microbial stability of formulations.

Growth of animal cells in culture, general procedure for cell culture; primary, established and transformed cell cultures.

Application of cell cultures in pharmaceutical industry and research.

Weight 230 g

Reviews

There are no reviews yet.

Be the first to review “PHARMACEUTICAL MICROBIOLOGY”